Weighting

The same modified market-capitalization weighting methodology which will be used to administer the NASDAQ® NeuroInsights® Neurotech Index was used as the basis for calculating its price history.

Components

The component list was derived from list of securities tracked by NeuroInsights with data sourced from FactSet Research Systems and NASDAQ, based on the Index Inclusion Criteria stated above. At each semi-annual reconstitution point, securities that commenced trading within the previous year were then included in the price history.

During the course of the back-test, the Index Inclusion Criteria were adjusted to ensure an adequate number of Index components during the back-test.

The June 2005 evaluation period volume requirement was lowered to 50,000 shares from 100,000 shares and the market capitalization requirement was lowered to $100 million from $200 million.

Number of Total Eligible and Included Index Components per Semi-Annual Evaluation:

June 2005: 31

December 2005: 29

June 2006: 29

December 2006: 32

June 2007: 33

Pricing

On 5/31/2005, the Index’s aggregate market value was calculated using prices on 5/31/2005 multiplied by the initial Index Shares as of 5/31/2005. The Index’s aggregate market value was then divided by an initial divisor chosen to set the initial Index Value to 100.00. Subsequently, Index Shares were rebalanced quarterly and the composition of the Index was re-adjusted semi-annually as described above. Upon each quarterly rebalancing and semi-annual reconstitution, a new Index aggregate market value was then calculated, with the divisor adjusted to ensure Index continuity.